Recently, we got a message from Mrs. Smith, having suffered from the side effects of hormone, asked for other treatment for her FSGS.Here is corresponding advices from nephrologist of Huaxia Kidney Disease Hospital. It is hoped to help others with the same trouble.
After diagnosed with FSGS, my doctor made me a therapeutic plan―persistant hormone treatment for 4 months. I began to take hormone drugs from 22th, July. One month later, urine protein decreased by 1.6g from 2.9g. However, three months passed by, it elevated by 2.5g. My doctors told me there was no choice but the increase of dosage. I heard that hormone drugs had side effects. I don’t want to take hormones any more. If I quit hormone, what’s other options for my FSGS ?
The answers from nephrologist form Huaxia Kidney Disease Hospital:
Not only for you, Mrs. Smith, many other patients with FSGS face the same trouble whether they can recover form the disease without hormone.
By far, a systematic treatment has not been found yet in clinic.
In terms of western medicine, hormone combination therapy is usually used in FSGS and about 30%~40% of patients get a remedy. But some other patients still worry about the side effects, especially their disease relapse easily after drug withdrawal. A better therapy without side effects has becoming same need for patients with FSGS .
Chinese Medicine iontophoresis , known as natural plants and herbs, provides another choice for patients.
How does Chinese Medicine iontophoresis treat FSGS?
hinese Medicine iontophoresis aims to block renal fibrosis, activate renal function of damaged intrinsic cells, at the same time, it provides necessary nutrition for repair process. Subsequently, these curative effects lay a good foundation to repair the damaged glomerular cells and restore its filter function. As an eventual result, patients with FSGS remedy from the root cause.
However, we should point out to you, Mrs. Smith. As you have accepted hormone treatment for a period of time, you should not quit it immediately. Hormone withdrawal has its own laws. If you break it, you will get punished―deterioration. The right steps you should take is to reduce the hormone gradually with the treatment of hinese Medicine iontophoresis at the same time. In this way, you get your possibility both in treating your FSGS and in getting rid of your hormone drugs.
2014年1月27日星期一
How to Make The Diagnosis of Glomerulonephritis
With the development of science, the way of diagnosis of glomerulonephritis become more and more. In the ancient time of China, the doctors mainly diagnose patients with five common ways: observation, answers and questions, smell, touch your pulses. However, now the doctors can use advanced devices and facilities to make a diagnosis.
But how to make a correct diagnosis? After the hospitalization, the patients with glomerulonephritis should take routine urine test two or three times a week, including the indexes of proteinuria, β2-microglobulin and so on. Bilateral renal ultrasound test and even biopsy.
In Huaxia Kidney Disease Hospital located in the world kite capital city-Weifang, has imported the most advanced equipment: ECT, which can make a very clearly diagnosis for glomerulonephritis. Kidney ECT is a kind of nuclear medicine instrument. It has the function of gamma imaging, mobile whole body imaging and computed tomography. All these functions enable ECT to reflect the change of Organ or Tissue Function, therefore, it will help the patients discover kidney disease in the early stage and provide precise data for the doctor.
But how to make a correct diagnosis? After the hospitalization, the patients with glomerulonephritis should take routine urine test two or three times a week, including the indexes of proteinuria, β2-microglobulin and so on. Bilateral renal ultrasound test and even biopsy.
In Huaxia Kidney Disease Hospital located in the world kite capital city-Weifang, has imported the most advanced equipment: ECT, which can make a very clearly diagnosis for glomerulonephritis. Kidney ECT is a kind of nuclear medicine instrument. It has the function of gamma imaging, mobile whole body imaging and computed tomography. All these functions enable ECT to reflect the change of Organ or Tissue Function, therefore, it will help the patients discover kidney disease in the early stage and provide precise data for the doctor.
Healthy Diet for Focal Segmental Glomerulosclerosis(FSGS)
Firstly, you should limit your intake of salt, because more intake of salt can make you feel frequent thirsty and need to drink much water. However, your kidneys have been damaged, so the function of expelling water is impaired. In case of taking much water, you are at risk of developing water retention, which will aggravate the edema.
Secondly, you had better arrange a low-protein diet. The exact meaning of this principle is low-quantity and high-quality protein. Limiting protein intake can decrease the waste product urea in your blood and eases the burdens of the kidneys. Therefore, you should avoid eating too much food like milk, cheese, yogurt, fish, meat or eggs, but high-protein foods like lean meat, milk, fish, egg white etc are ok. Beans and bean products contain much inferior protein, so they should also be avoided.
Thirdly, you should restrict fatty and greasy food. Much intake of them can increase your risk of some FSGS complications, such as high cholesterol level, high blood pressure and so on.
Fourthly, stimulating foods like sea food, spicy food, beef, mutton, crabs, garlic, onions, parsley, dog meat and wine, coffee, seasoning and so on should be avoided.
If your FSGS has progressed to Renal Failure, low-potassium and low-phosphorus diets are necessary. High potassium foods include banana, date, potato, spinach, mushroom and so on. Phosphorous is high is foods like animal liver, yolk, tea, peanut, walnut, sesame, etc. Therefore, these foods should be avoided.
Secondly, you had better arrange a low-protein diet. The exact meaning of this principle is low-quantity and high-quality protein. Limiting protein intake can decrease the waste product urea in your blood and eases the burdens of the kidneys. Therefore, you should avoid eating too much food like milk, cheese, yogurt, fish, meat or eggs, but high-protein foods like lean meat, milk, fish, egg white etc are ok. Beans and bean products contain much inferior protein, so they should also be avoided.
Thirdly, you should restrict fatty and greasy food. Much intake of them can increase your risk of some FSGS complications, such as high cholesterol level, high blood pressure and so on.
Fourthly, stimulating foods like sea food, spicy food, beef, mutton, crabs, garlic, onions, parsley, dog meat and wine, coffee, seasoning and so on should be avoided.
If your FSGS has progressed to Renal Failure, low-potassium and low-phosphorus diets are necessary. High potassium foods include banana, date, potato, spinach, mushroom and so on. Phosphorous is high is foods like animal liver, yolk, tea, peanut, walnut, sesame, etc. Therefore, these foods should be avoided.
Why FSGS Patients Have Poor Appetite and Nausea
Poor appetite and nausea in FSGS are two common symptoms. If you want to know the causes, please reading following words.
The causes of poor appetite and nausea in FSGS
As the different situations the patients face to, the degree of the poor appetite and nausea are also different. As the decline of the kidney function, blood urea nitrogen elevated, urea enzymes resolve urea into ammonia in intestinal tract, which will stimulate gastrointestinal mucosa and cause nausea, vomiting. As a conclusion, the reason why FSGS patients suffer from poor appetite and nausea is that an increased BUN. For FSGS patients, kidneys function declined, patient urine frequently and the amount of urine at night get more. Due to too much water lost at night, so next morning, FSGS patients will suffer a high level of urea and this also leads to serious vomit in the morning.
The causes of poor appetite and nausea in FSGS
As the different situations the patients face to, the degree of the poor appetite and nausea are also different. As the decline of the kidney function, blood urea nitrogen elevated, urea enzymes resolve urea into ammonia in intestinal tract, which will stimulate gastrointestinal mucosa and cause nausea, vomiting. As a conclusion, the reason why FSGS patients suffer from poor appetite and nausea is that an increased BUN. For FSGS patients, kidneys function declined, patient urine frequently and the amount of urine at night get more. Due to too much water lost at night, so next morning, FSGS patients will suffer a high level of urea and this also leads to serious vomit in the morning.
Proteinuria and Nausea in FSGS Patients
For patients who suffer from FSGS, proteinuria and nausea are very common symptoms in their body. I would like to share some information about proteinuria and nausea in FSGS patients.
Protein is an important index to reflect the glomerulus and kidney tubes. Kidney tubes will influence the reabsorption of protein. When there are damages in FSGS patients’ kidneys, the protein will lean out within the urine. Then proteinuria will occur in FSGS patients.
Why do patients with FSGS have nausea?
1. Application cyclophosphamide. FSGS Patients often feel nausea, vomiting after they used cyclophosphamide. Cyclophosphamide will damage the liver function. This can be tested from medical history and liver function index.
2. If patients in FSGS use application diuretics for Long-term in not appropriate way, when they have Hyponatremia, they can appear nausea and vomiting.
3. Metabolic acidosis. FSGS patients with acid metabolites can′t be lean out normally, and accumulated toxics lead to acidosis in patients body. It can be measured by blood pH and can be known by carbon dioxide binding force. FSGS Patients can appear when they have acidosis sigh, nausea and vomiting breath problems will attack them.
4. Inflammation or gastrointestinal mucosa ulcer in end stage of FSGS patients. Renal impairment form the stomach secrete stomach acid, which can lead to digest function disorder, nausea vomiting.
As for the treatment, we can recommend you Immunotherapy of Huaxia Kidney Disease Hospital, which can release the Proteinuria and nausea in FSGS patients greatly. What is more, Immunotherapy of Huaxia Kidney Disease Hospitalcan replace the intrinsic cells in our body. Our kidney function can be renewed completely. So it can help us solve the problems Proteinuria and nausea in FSGS patients.
Protein is an important index to reflect the glomerulus and kidney tubes. Kidney tubes will influence the reabsorption of protein. When there are damages in FSGS patients’ kidneys, the protein will lean out within the urine. Then proteinuria will occur in FSGS patients.
Why do patients with FSGS have nausea?
1. Application cyclophosphamide. FSGS Patients often feel nausea, vomiting after they used cyclophosphamide. Cyclophosphamide will damage the liver function. This can be tested from medical history and liver function index.
2. If patients in FSGS use application diuretics for Long-term in not appropriate way, when they have Hyponatremia, they can appear nausea and vomiting.
3. Metabolic acidosis. FSGS patients with acid metabolites can′t be lean out normally, and accumulated toxics lead to acidosis in patients body. It can be measured by blood pH and can be known by carbon dioxide binding force. FSGS Patients can appear when they have acidosis sigh, nausea and vomiting breath problems will attack them.
4. Inflammation or gastrointestinal mucosa ulcer in end stage of FSGS patients. Renal impairment form the stomach secrete stomach acid, which can lead to digest function disorder, nausea vomiting.
As for the treatment, we can recommend you Immunotherapy of Huaxia Kidney Disease Hospital, which can release the Proteinuria and nausea in FSGS patients greatly. What is more, Immunotherapy of Huaxia Kidney Disease Hospitalcan replace the intrinsic cells in our body. Our kidney function can be renewed completely. So it can help us solve the problems Proteinuria and nausea in FSGS patients.
Exercise for Chronic Glomerulonephritis Patients
When can chronic glomerulonephritis patients do exercise?
Doing physical exercise regularly enables to strengthen muscles and improve immunity. In this case, as long as chronic glomerulonephritis patients are not badly weak and have sports taboos due to multiple organ renal failure, glomerulonephritis patients are recommended to do some exercise. Though the therapy of chronic glomerulonephritis needs patients to have enough rest and not be overtired, they should not oppose the healthy benefits of moderate exercise. In fact, moderate exercise not only build up their body, promote their integration with society, but also is more helpful for their therapy. For example, moderate exercise can alleviate high blood pressure, hyperlipidemia and high blood sugar control so as to maintain a healthy weight and further prevent vascular embolism diseases.
What chronic glomerulonephritis patients should not do?
However, doing exercise must be in a moderate range and the standard for chronic glomerulonephritis patients is no feeling of overtired. On one hand, chronic glomerulonephritis patients had better choose aerobic exercise and should not do strenuous exercise. In this case, if you want to know what exercise is fit for you, you can tell your conditions to our online doctor and the doctor will recommend some suitable sports for you according to your condition. On the other hand, in Chronic Glomerulonephritis, damaged kidneys usually lead to high creatinine level, proteinuria and blood in urine. In this case, if you do strenuous exercise, creatinine level increases further. The most important one is that strenuous exercise will burden your kidneys which will aggravate proteinuria and hematuria. If all these symptoms are not under control, they will speed up the progression into renal failure. In this condition, you are facing dialysis or kidney transplant to extend your life span.
Chronic Glomerulonephritis patients can do some moderate exercise which is helpful for their health and treatment. Besides, chronic glomerulonephritis should avoid strenuous exercise.
Doing physical exercise regularly enables to strengthen muscles and improve immunity. In this case, as long as chronic glomerulonephritis patients are not badly weak and have sports taboos due to multiple organ renal failure, glomerulonephritis patients are recommended to do some exercise. Though the therapy of chronic glomerulonephritis needs patients to have enough rest and not be overtired, they should not oppose the healthy benefits of moderate exercise. In fact, moderate exercise not only build up their body, promote their integration with society, but also is more helpful for their therapy. For example, moderate exercise can alleviate high blood pressure, hyperlipidemia and high blood sugar control so as to maintain a healthy weight and further prevent vascular embolism diseases.
What chronic glomerulonephritis patients should not do?
However, doing exercise must be in a moderate range and the standard for chronic glomerulonephritis patients is no feeling of overtired. On one hand, chronic glomerulonephritis patients had better choose aerobic exercise and should not do strenuous exercise. In this case, if you want to know what exercise is fit for you, you can tell your conditions to our online doctor and the doctor will recommend some suitable sports for you according to your condition. On the other hand, in Chronic Glomerulonephritis, damaged kidneys usually lead to high creatinine level, proteinuria and blood in urine. In this case, if you do strenuous exercise, creatinine level increases further. The most important one is that strenuous exercise will burden your kidneys which will aggravate proteinuria and hematuria. If all these symptoms are not under control, they will speed up the progression into renal failure. In this condition, you are facing dialysis or kidney transplant to extend your life span.
Chronic Glomerulonephritis patients can do some moderate exercise which is helpful for their health and treatment. Besides, chronic glomerulonephritis should avoid strenuous exercise.
2014年1月24日星期五
Will IgA Nephropathy Lead to FSGS
IgA Nephropathy is one primary glomerular disease that is due to different factors. In most cases, IgA Nephropathy is characterized by the deposition of polymer IgA (PIgA) along with C3, IgG and IgM. It means abnormal IgA immune system leads to the presence of PIgA in circulatory system and its deposition in glomerular mesangial area. In addition, the onset of IgA Nephropathy may also have a link with bone marrow and inflammatory factors secreted by mesangial cells.
According to pathologic changes, IgA Nephropathy is divided into five classes. Generally, most glomeruli and renal tubules are not damaged in the early stage. However, as the condition progresses, the IgA deposition will cause more and more damage to glomeruli and renal tubules. During this process, FSGS occurs easily and symptoms as follows can help us detect FSGS early.
1. Proteinuria
2. Swelling around in eyes, hands and feet and it may be painful
3. High blood pressure
4. Hematuria, especially microscopic hematuria
5. High cholesterol level
If you are diagnosed with IgA Nephropathy and have one or more symptoms the above mentioned, Huaxia kidney Disease Hospital experts here suggest you to do a kidney biopsy to see whether you also have FSGS. Making an accurate diagnosis is a must to guarantee you accept an effective treatment.
For people whose FSGS is due to IgA Nephropathy, steroid like cortisone and immunosuppressive agents like cyclosporin are commonly used to control their condition. However, if their FSGS and IgA Nephropathy are too serious to be treated by these medicines, The Hot Compress Therapy of Huaxia Kidney Disease Hospital will be recommended.
According to pathologic changes, IgA Nephropathy is divided into five classes. Generally, most glomeruli and renal tubules are not damaged in the early stage. However, as the condition progresses, the IgA deposition will cause more and more damage to glomeruli and renal tubules. During this process, FSGS occurs easily and symptoms as follows can help us detect FSGS early.
1. Proteinuria
2. Swelling around in eyes, hands and feet and it may be painful
3. High blood pressure
4. Hematuria, especially microscopic hematuria
5. High cholesterol level
If you are diagnosed with IgA Nephropathy and have one or more symptoms the above mentioned, Huaxia kidney Disease Hospital experts here suggest you to do a kidney biopsy to see whether you also have FSGS. Making an accurate diagnosis is a must to guarantee you accept an effective treatment.
For people whose FSGS is due to IgA Nephropathy, steroid like cortisone and immunosuppressive agents like cyclosporin are commonly used to control their condition. However, if their FSGS and IgA Nephropathy are too serious to be treated by these medicines, The Hot Compress Therapy of Huaxia Kidney Disease Hospital will be recommended.
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