What are the Causes of Chronic Renal Failure

There are a variety of diseases and pathological conditions that can cause chronic renal failure. The following are the main causes.

glomerular diseases including IgA nephropathy, FSGS, diabetic nephropathy, hypertensive nephropathy, lupus nephritis, etc.

chronic pyelonephritis, uric acid nephropathy, obstructive nephropathy as well as kidney damages due to long term intake of certain drugs such as aristolochic acid nephropathy.

renal vascular diseases such as aneurysm, renal artery embolization, renal thrombus and renal arteriovenous fistula, etc.

hereditary kidney diseases such as polycystic kidney disease(PKD) and hereditary nephritis, etc.

Diabetic nephropathy and hypertensive arteriolosclerosis and in developing countries these two causes still follow primary glomerulonephritis. Ischemic nephropathy due to bilateral renal artery stenosis or occlusion is one important cause of chronic renal failure especially in elderly patients.