2014年1月27日星期一

What's The Stage of Hypertension Nephropathy

In clinic, nephrotic hypertension is divided into three stages in terms of patient’s condition and their lab values.

Stage I―Micro-Albumin Stage. In this stage, it is characterized with the anomaly of urinary albumin excretion rate. Renal function is in the normal level; urine protein is negative.

Stage II―Clinical Urine Protein Stage. Urine protein is positive; 24-hour total urine protein rate>0.5; normal renal function.

Stage III―Renal Insufficiency Stage. It is characterized with the decrease of Creatinine Clearance Rate and the increase of Serum Creatinine . It is divided into non-dialysis stage .

How to diagnose Nephrotic Hypertension?

Medical History: the age of onset is about 40~50 years old, the history of hypertension is more than 5~10 years. At the early stage, patients may only feel frequent urination at night and then proteinuria. In some special cases, they may find temporal gross Hematuria because of capillary rupture and accompanied with unobvious backache. Patients may follows with other diseases, such as arteriosclerotic retinopathy, leftventricular hypertrophy, coronary disease, heart failure, cerebral arteriosclerosis or cranial vascular disease.

With illness condition deteriorating, it can develop into renal failure, renal injury or abnormality of urination. If diastolic pressure is more than 16Kpa, patients usually appear to have obvious cardio-cerebral complications which progresses rapidly in a short time. Meantime, patients suffer from a large quantity of proteinuria accompanied by Hematuria and renal function decline.

Physical Tests: blood pressure level keeps rising , dropsy in eyes or legs; arteriosclerotic retinopathy.

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