2014年1月27日星期一

What are the Causes of Rapidly Progressive Nephritis

1, type one: anti-globule basement membrane nephritis, which symptoms are IgA and complement in blood serum C, they will be precipitation like grain sample along glomerular capillary wall.

2, Type two: immune complex nephritis and its symptoms are IgA and C3 been precipitation like grain sample along glomerular capillary wall.

Aiming at those two typical causes of rapidly progressive nephritis, The Hot Compress Therapy of Huaxia Kidney Disease Hospital will be your best choice. Huaxia Kidney Disease Hospital is a specialized kidney disease hospital, its Huaxia Therapy starts a unique way to treat rapidly progressive nephritis. The theory of Huaxia Therapy for Kidney Disease Traditional Chinese medicine iontophoresis is that the drug is dissociated into ion under the effect of direct magnetoelectricity, the negative ion and positive ion are guiding into a specifically place. I can not describe it specifically, because it is really so deeply that I can not explain it with my own words.

What is Rapidly Progressive Nephritis

Rapidly progressive nephritis has not been a strang word for a large number of people, however, once refer this word, people always fear it. Why people still fear it, what do you know about it and how much do you know about it?

The reason you fear it is because you know little about it and exist so many misunderstandings, so knowing as much as knowledge about rapidly progressive nephritis is really good for patients’ condition. Few people know that the condition of onset and severity have the same symptoms, such as edema, hematuria, proteinuria and high blood pressure, and also exist oliguria and even anuria. The difference from acute nephritis is no recovery without treatment, sometimes acute nephritis can be cured by itself. What if correct treatment is not taken, rapidly progressive will develop into end stage kidney failure, and patients can not survive without dialysis.

As far as concerned above statement, diagnosis become very important. Only correct diagnosis can give patients right treatment methods, aiming at this point, Huaxia Kidney Disease Hospital import the most advanced equipment - ECT to diagnose kidney disease, which has no suffer and trauma. The Immunotherapy of Huaxia Kidney Disease Hospital also has opened up a now field for kidney disease patients, for rapidly progressive nephritis, and also starts a unique way to treat kidney disease and rapidly progressive nephritis.

Hormone and FSGS(Focal Segmental Glomerulosclerosis)

Recently, we got a message from Mrs. Smith, having suffered from the side effects of hormone, asked for other treatment for her FSGS.Here is corresponding advices from nephrologist of Huaxia Kidney Disease Hospital. It is hoped to help others with the same trouble.

After diagnosed with FSGS, my doctor made me a therapeutic plan―persistant hormone treatment for 4 months. I began to take hormone drugs from 22th, July. One month later, urine protein decreased by 1.6g from 2.9g. However, three months passed by, it elevated by 2.5g. My doctors told me there was no choice but the increase of dosage. I heard that hormone drugs had side effects. I don’t want to take hormones any more. If I quit hormone, what’s other options for my FSGS ?

The answers from nephrologist form Huaxia Kidney Disease Hospital:

Not only for you, Mrs. Smith, many other patients with FSGS face the same trouble whether they can recover form the disease without hormone.

By far, a systematic treatment has not been found yet in clinic.

In terms of western medicine, hormone combination therapy is usually used in FSGS and about 30%~40% of patients get a remedy. But some other patients still worry about the side effects, especially their disease relapse easily after drug withdrawal. A better therapy without side effects has becoming same need for patients with FSGS .

Chinese Medicine iontophoresis , known as natural plants and herbs, provides another choice for patients.

How does Chinese Medicine iontophoresis treat FSGS?

hinese Medicine iontophoresis aims to block renal fibrosis, activate renal function of damaged intrinsic cells, at the same time, it provides necessary nutrition for repair process. Subsequently, these curative effects lay a good foundation to repair the damaged glomerular cells and restore its filter function. As an eventual result, patients with FSGS remedy from the root cause.

However, we should point out to you, Mrs. Smith. As you have accepted hormone treatment for a period of time, you should not quit it immediately. Hormone withdrawal has its own laws. If you break it, you will get punished―deterioration. The right steps you should take is to reduce the hormone gradually with the treatment of hinese Medicine iontophoresis at the same time. In this way, you get your possibility both in treating your FSGS and in getting rid of your hormone drugs.

How to Make The Diagnosis of Glomerulonephritis

With the development of science, the way of diagnosis of glomerulonephritis become more and more. In the ancient time of China, the doctors mainly diagnose patients with five common ways: observation, answers and questions, smell, touch your pulses. However, now the doctors can use advanced devices and facilities to make a diagnosis.

But how to make a correct diagnosis? After the hospitalization, the patients with glomerulonephritis should take routine urine test two or three times a week, including the indexes of proteinuria, β2-microglobulin and so on. Bilateral renal ultrasound test and even biopsy.

In Huaxia Kidney Disease Hospital located in the world kite capital city-Weifang, has imported the most advanced equipment: ECT, which can make a very clearly diagnosis for glomerulonephritis. Kidney ECT is a kind of nuclear medicine instrument. It has the function of gamma imaging, mobile whole body imaging and computed tomography. All these functions enable ECT to reflect the change of Organ or Tissue Function, therefore, it will help the patients discover kidney disease in the early stage and provide precise data for the doctor.

Healthy Diet for Focal Segmental Glomerulosclerosis(FSGS)

Firstly, you should limit your intake of salt, because more intake of salt can make you feel frequent thirsty and need to drink much water. However, your kidneys have been damaged, so the function of expelling water is impaired. In case of taking much water, you are at risk of developing water retention, which will aggravate the edema.

Secondly, you had better arrange a low-protein diet. The exact meaning of this principle is low-quantity and high-quality protein. Limiting protein intake can decrease the waste product urea in your blood and eases the burdens of the kidneys. Therefore, you should avoid eating too much food like milk, cheese, yogurt, fish, meat or eggs, but high-protein foods like lean meat, milk, fish, egg white etc are ok. Beans and bean products contain much inferior protein, so they should also be avoided.

Thirdly, you should restrict fatty and greasy food. Much intake of them can increase your risk of some FSGS complications, such as high cholesterol level, high blood pressure and so on.

Fourthly, stimulating foods like sea food, spicy food, beef, mutton, crabs, garlic, onions, parsley, dog meat and wine, coffee, seasoning and so on should be avoided.

If your FSGS has progressed to Renal Failure, low-potassium and low-phosphorus diets are necessary. High potassium foods include banana, date, potato, spinach, mushroom and so on. Phosphorous is high is foods like animal liver, yolk, tea, peanut, walnut, sesame, etc. Therefore, these foods should be avoided.

Why FSGS Patients Have Poor Appetite and Nausea

Poor appetite and nausea in FSGS are two common symptoms. If you want to know the causes, please reading following words.

The causes of poor appetite and nausea in FSGS

As the different situations the patients face to, the degree of the poor appetite and nausea are also different. As the decline of the kidney function, blood urea nitrogen elevated, urea enzymes resolve urea into ammonia in intestinal tract, which will stimulate gastrointestinal mucosa and cause nausea, vomiting. As a conclusion, the reason why FSGS patients suffer from poor appetite and nausea is that an increased BUN. For FSGS patients, kidneys function declined, patient urine frequently and the amount of urine at night get more. Due to too much water lost at night, so next morning, FSGS patients will suffer a high level of urea and this also leads to serious vomit in the morning.

Proteinuria and Nausea in FSGS Patients

For patients who suffer from FSGS, proteinuria and nausea are very common symptoms in their body. I would like to share some information about proteinuria and nausea in FSGS patients.

Protein is an important index to reflect the glomerulus and kidney tubes. Kidney tubes will influence the reabsorption of protein. When there are damages in FSGS patients’ kidneys, the protein will lean out within the urine. Then proteinuria will occur in FSGS patients.

Why do patients with FSGS have nausea?

1. Application cyclophosphamide. FSGS Patients often feel nausea, vomiting after they used cyclophosphamide. Cyclophosphamide will damage the liver function. This can be tested from medical history and liver function index.

2. If patients in FSGS use application diuretics for Long-term in not appropriate way, when they have Hyponatremia, they can appear nausea and vomiting.

3. Metabolic acidosis. FSGS patients with acid metabolites can′t be lean out normally, and accumulated toxics lead to acidosis in patients body. It can be measured by blood pH and can be known by carbon dioxide binding force. FSGS Patients can appear when they have acidosis sigh, nausea and vomiting breath problems will attack them.

4. Inflammation or gastrointestinal mucosa ulcer in end stage of FSGS patients. Renal impairment form the stomach secrete stomach acid, which can lead to digest function disorder, nausea vomiting.

As for the treatment, we can recommend you Immunotherapy of Huaxia Kidney Disease Hospital, which can release the Proteinuria and nausea in FSGS patients greatly. What is more, Immunotherapy of Huaxia Kidney Disease Hospitalcan replace the intrinsic cells in our body. Our kidney function can be renewed completely. So it can help us solve the problems Proteinuria and nausea in FSGS patients.

Exercise for Chronic Glomerulonephritis Patients

When can chronic glomerulonephritis patients do exercise?

Doing physical exercise regularly enables to strengthen muscles and improve immunity. In this case, as long as chronic glomerulonephritis patients are not badly weak and have sports taboos due to multiple organ renal failure, glomerulonephritis patients are recommended to do some exercise. Though the therapy of chronic glomerulonephritis needs patients to have enough rest and not be overtired, they should not oppose the healthy benefits of moderate exercise. In fact, moderate exercise not only build up their body, promote their integration with society, but also is more helpful for their therapy. For example, moderate exercise can alleviate high blood pressure, hyperlipidemia and high blood sugar control so as to maintain a healthy weight and further prevent vascular embolism diseases.

What chronic glomerulonephritis patients should not do?

However, doing exercise must be in a moderate range and the standard for chronic glomerulonephritis patients is no feeling of overtired. On one hand, chronic glomerulonephritis patients had better choose aerobic exercise and should not do strenuous exercise. In this case, if you want to know what exercise is fit for you, you can tell your conditions to our online doctor and the doctor will recommend some suitable sports for you according to your condition. On the other hand, in Chronic Glomerulonephritis, damaged kidneys usually lead to high creatinine level, proteinuria and blood in urine. In this case, if you do strenuous exercise, creatinine level increases further. The most important one is that strenuous exercise will burden your kidneys which will aggravate proteinuria and hematuria. If all these symptoms are not under control, they will speed up the progression into renal failure. In this condition, you are facing dialysis or kidney transplant to extend your life span.

Chronic Glomerulonephritis patients can do some moderate exercise which is helpful for their health and treatment. Besides, chronic glomerulonephritis should avoid strenuous exercise.

Diet Plan for Hypertension Nephropathy

1. Food with high content of potassium is good for those who have high blood pressure but have normal kidney function. Potassium can be used to balance sodium.

Food rich in potassium are: soybean, red bean, tomato, celery, mushroom, green vegetables; fruits such as orange, apple, banana, pear, kiwi fruit, pineapple, persimmon, nut, watermelon.

Some food with much calcium and less sodium are good choice, including potato, eggplant, kelp, asparagus lettuce, etc.; and milk, yogurt, dried small shrimp an other food with much calcium.

Broth stewed with meat need to be avoided, because there is much nitrogen in the soup which will promote the uric acid and aggravate the burden to heart, liver and kidneys.

2. Limit the intake of salt. The total intake of salt in a day need to be less than 6g if you have high blood pressure. It can be measured by means of a cover of bear bottle, and one bottle of salt is just about 6g. The total intake refers to the salt in all the meals as well as in other food with contain sodium. Less sodium will contribute to the lowering of blood pressure.

One thing worth mentioning is the natural content of sodium in food such as meat, fish, egg and milk are all included in the 6g/d standard, so when they cook, they can even put in little salt, since those sodiums in food naturally is adequate. If the blood pressure is too high, or there is obvious edema with the sufferer, they need to take in no salt at all.

3. When cooking, vegetable oil is preferred. Marine fish is a good choice for those people who have high blood pressure but have no insufficiency of kidney function, because it can reduce the plasma cholesterol and have the ability to prevent the form of thrombus and stroke. It also has much linoleic acid, so it can increase the elasticity of blood vessels to prevent the rupture of them and avoid the complications of high blood pressure. However, all the seafood are irritant, so when you eat, you should ask for your doctors′ advices in advance and have a better choice according to the individual condition of disease.

4.Low-sugar diet is favorable. Sweet food contains much sugar, which can transform into fat and accumulate in the blood vessels, so low-sugar diet can be beneficial to the prevention of arteriosclerosis.

What's The Stage of Hypertension Nephropathy

In clinic, nephrotic hypertension is divided into three stages in terms of patient’s condition and their lab values.

Stage I―Micro-Albumin Stage. In this stage, it is characterized with the anomaly of urinary albumin excretion rate. Renal function is in the normal level; urine protein is negative.

Stage II―Clinical Urine Protein Stage. Urine protein is positive; 24-hour total urine protein rate>0.5; normal renal function.

Stage III―Renal Insufficiency Stage. It is characterized with the decrease of Creatinine Clearance Rate and the increase of Serum Creatinine . It is divided into non-dialysis stage .

How to diagnose Nephrotic Hypertension?

Medical History: the age of onset is about 40~50 years old, the history of hypertension is more than 5~10 years. At the early stage, patients may only feel frequent urination at night and then proteinuria. In some special cases, they may find temporal gross Hematuria because of capillary rupture and accompanied with unobvious backache. Patients may follows with other diseases, such as arteriosclerotic retinopathy, leftventricular hypertrophy, coronary disease, heart failure, cerebral arteriosclerosis or cranial vascular disease.

With illness condition deteriorating, it can develop into renal failure, renal injury or abnormality of urination. If diastolic pressure is more than 16Kpa, patients usually appear to have obvious cardio-cerebral complications which progresses rapidly in a short time. Meantime, patients suffer from a large quantity of proteinuria accompanied by Hematuria and renal function decline.

Physical Tests: blood pressure level keeps rising , dropsy in eyes or legs; arteriosclerotic retinopathy.

can Kidney Disease Cause High Blood Pressure

As we know, many patients with kidney disease will always complain of dizziness, headache and any other symptoms. The patients have these symptoms may be due to their high blood pressure. Then why will kidney diseases will cause high blood pressure?

First we need to make one definition clear-what is Renin? Renin, also known as angiotensinogenase-a kind of acidic proteinase, is an enzyme that participates in the body′s renin-angiotensin system , which will be involved in later. It is secreted by the kidney, or by specialized cells called granular cells of the juxtaglomerular apparatus, to be exact. The renin enzyme circulates in the blood stream and cleaves angiotensinogen secreted from the liver to yield peptide angiotensin I. Under normal condition, little renin is secreted and so is the angiotensin in the blood, which does not affect the blood pressure obviously. Angiotensin, as its name implies, can constrict blood vessels potently, which, however, would not participate in regulation of blood pressure directly under normal conditions. When blood volume in circulation decreases because of the body’ loss of blood, or when blood flow in the kidney is reduced due to kidney disease, Angiotensin will become more in the blood significantly, which has certain effects in maintaining circulating blood volume and arterial blood pressure. As to patients with kidney disease, inflammatory reaction, compression on surrounding tissues, obstruction or other causes inside the kidney will cause insufficient supply of oxygen and blood, which will decrease blood flow of kidney, thus stimulating secretion of rennin by granular cells, as we had mentioned before. Then the renin cleaves angiotensinogen secreted from the liver into the peptide angiotensin I after entering into blood circulation, which we also said before. Angiotensin I is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. Then, part of the angiotensin II, under the effect of angiotoninase A in plasma and tissue fluid, is cleaved to angiotensin III.

Angiotensin I can stimulate secretion of Epinephrine by Adrenal Medella, which, can increase heart rate and constricts blood vessels. However, Angiotensin I, itself can not constrict blood vessels directly and significantly. Compared with Angiotensin I, Angiotensin II is the most vasoactive peptide and is a potent constrictor of all blood vessels, which can cause the blood pressure to rise.

4 Way Prevent Hypertension into Kidney Failure

1. If the patients aged above 40 and 50 years old whose history of Hypertension is above 5 and 10 years are diagnosed albumin increase, they should be alert.

2. When night urine increasing, suffering from proteinuria or transient hematuria, the patients should check kidney frequently. Besides, when urinary protein is qualitative and 24 hours urinary protein is quantitative, the patients should pay attention to measure blood pressure and do fundus examination.

3. Keep defecation unobstructed.

4. Avoid contacting with heavy metals, toxicant and the drugs that possibly damage the kidney.

Why IgA Nephropathy Patients Get Hypertention Nephropathy

IgA Nephropathy is the most common of glomerulonephritis in the world, which is characterized by predominant IgA deposition in the glomerular messangium. With the development of illness condition, some IgA Nephropathy patients get Nephrotic Hypertention.

With the progression of IgA Nephropathy, the renal intrinsic cells can be damaged and kidney dysfunction occurs. Water and sodium retention appears, so the kidney blood vessels are compressed, and blood flow decreases. Then renal receptor will secrete more renin, and then angiotensin concentration increases, which make blood vessel shrink, thus increasing the blood pressure. High blood pressure and renal injury may aggravate each other. In general, if IgA Nephropathy patients get hypertension, their renal function is about to be injured has already been injured.

Once patients of IgA Nephropathy have symptoms of Nephrotic Hypertension, they should receive effective treatment instead of self-medication. IgA Nephropathy led hypertension is different from primary hypertension. The key of treating hypertension is to treat IgA Nephropathy through methods of delaying or blocking renal fibrosis. Only in this way, can we treat hypertension radically.

The Hot Compress Therapy of Huaxia Kidney Disease Hospital can not only treat IgA Nephropathy from the root by degrading the IgA deposits but also restore the renal function. Once injured kidney is recovered, IgA Nephropathy can be relieved and hypertension caused by IgA Nephropathy can also be relieved.

Differences Between Hypertension Nephropathy and Primary Hypertension

What is Nephrotic Hypertention?

Nephrotic Hypertension, one important part of secondary high blood pressure is a disorder caused by kidney disease. One type is renovascular hypertension caused by the renal ischemia due to renal artery narrowing. Another type is renal parenchymal hypertension caused by renal diseases.

Renovascular hypertension: Patients mostly get the disorder before 30 years old or after 50 years old. In clinic, there may appears hypertension rapidly getting worsen. A part of patients may have back injury and bellyache history. For patients, the blood pressure can not be control well with hypotensor. As getting an examination for body, vascular murmur can be heard in the upper abdominal. The size of two kidneys is different through the X-ray and abdominal ultrasound scan.

Renal Hypertension: Patients develop the disorder at an early age who have the Nephritis or Pyelonephritis history. Some symptoms may occur like hematuria, edema, protein urine, or fever, back injure, frequent micturition, urgent micturition and dysuria urodynia etc. Before the onset of renal Hypertension, patients may be with or without renal damage.

How to distinguish Nephrotic Hypertention from primary Hypertension?

Hypertension or high blood pressure is a cardiac chronic medical condition in which the systemic arterial blood pressure is elevated.

Primary Hypertension: The statistics show that 80-90 percent of Hypertention is primary high blood pressure, only 10-20 percent secondary high blood pressure. As for the causes of primary high blood pressure also called Hypertension, it is still exactly unknown. The primary high blood pressure usually occur in middle-aged and elderly people over 40 year-old most of whom have hypertensive family history.

Symptoms:

High blood pressure rises rapidly to a high level;

Slight edema ;

Usually, abnormal urine examines follow high blood pressure.

There is no obvious urine change and renal damage at the early stage of Hypertention.

Nephrotic Hypertention: It is a secondary high blood pressure caused by renal disease. Its onset is usually in patients under 30 year-old not having hypertensive family history. Patients with Nephrotic Hypertention usually have edema and gradually elevated blood pressure. And sometimes blood pressure is likely to worsen rapidly. Urinary change and renal damage are obvious for patients with Nephrotic Hypertention. Hypertention follows the abnormal urine examines.

Renal Failure and High Blood Pressure

If the patients with Hypertensive can't be cured timely and accurately, they may suffer from renal failure.

The patients with Hypertensive can′t be cured timely and accurately, which will destroy renal blood vessels, leading to the insufficient of renal blood supply and then cause the kidney function damage. When renal function is completely lost, the patients will suffer from kidney failure.

At this point, the kidney will not release enough hormone needed which is used to maintain blood pressure balance and manufacture erythrocyte and vitamin D. Thus, the following symptoms will be showed:

1. Raised blood pressure: causing serious complications such as stroke, heart disease and even death.

2. The body can′t produce enough erythrocytes, which leads to renal anemia.

3. Due to the lack of calcium, bone will become fragile.

4. What′s more, the excess liquid, waste and toxin will accumulate in the body. The blood accumulation overmuch will lead to irreparable damage. In order to continue life, the patients often need dialysis or renal transplantation.

Natural Remedies for Hypertensive Nephropathy

1. Traditional Chinese medicine iontophoresis

This can dilate blood vessels, decrease coagulation and blood viscosity, decompose immune complex, restrain the release of inflammatory factors, This is given externally, neither operation nor oral medication. Patient can take this treatment by lying on their bed, the active ingredients can penetrate into kidneys through urinary bladder channel in waist areas. By this treatment, a favorable internal environment can be provided so the aggravation of your kidney function can be halted or slowed down.

2.The Hot Compress Therapy of Huaxia Kidney Disease Hospital

When kidney gets damaged, massive toxins can not be removed timely and mess up in your body, so your immunity can be in disorder. Massive abnormal immune reaction can happen and rev up the aggravation of your renal function. We adopt effective western medicine to stop the abnormal immune reaction, so that we can get more time for next improvement treatment.

3.Blood Purification

With the decrease of renal function, large amount toxins can′t be removed by the kidney timely, which can impair other organs in body. Therefore it is quite necessary to cleanse the blood. We can provide standard hemodialysis but also plasma exchange.

How to Treat Hypertensive Nephropathy

How to Treat Hypertensive Nephropathy to Get a Good Curative Effect? The experts in Huaxia Kidney Disease Hospital say that Hypertensive nephropathy is the complication of high blood pressure. The key of treatment is to control high blood pressure and repair the damaged renal inherent cells. Only in this way, can the patients get better clinical effect.

How to Treat Hypertensive Nephropathy to Get a Good Curative Effect? The occurrence of Hypertensive Nephropathy is related with the severity of hypertension and continuous time. At the same time, it also influenced by drinking, diabetes, hyperlipidemia and hyperuricemia. High blood pressure can lead to kidney damage, in turn, kidney damage will also aggravate the hypertension. During the treatment process, step-down treatment is particularly important. The patients are advised to treat through combining traditional Chinese and western medicine, which can not only improve all levels of blood vessels through the drug treatment, fundamentally, lower blood pressure but also repair the damaged renal unit and improve renal function.

The expert of Huaxia Kidney Disease Hospital reminds hypertension patients that they should closely monitor the blood pressure condition, at the same time, they also should go to a hospital to make regular urine routine inspection to prevent hypertension nephropathy.

How to Improve the Prognosis of Hypertension Nephropathy

1.Lose weight

You′re suggested to control your weight and reach the goal of being lower than 24kg/m2

2.Take balance diet

(a)How much salt do you take each day? WHO advise you to take no more than 6g each day. If you haven′t reach that standard, then reduce it immediately. Firstly, use less salt when cooking. Secondly, eat less salty foods like pickles.

(b)Reduce intake of dietary fat, eat more vegetables and fruits, and supplement some proper high-quality protein but not much. It′s adviced that fat occupies less than 30% in the total calories and saturated fat counts less than 10%; Protein counts for about 15% in the total calories and animal protein couts less than 20% in the total protein.

(c)Limit the intake of alcohol drinks

Hypertension patients are suggested to quit alcohol drinking because alcolhol could increase body′s resistance to the medicines they take. If you are a drinker, you should stop drinking as soon as possible. A healthy man shouldn′t drink more than 20-30g per day, a woman should not drink 10-15g plus each day.

3.Increase physical exercises

Physical exercises could not only reduce blood pressure, but it′s also in favor of losing weight, increase strength, and reducing insulin resistance. Patients should choose right exercise methods according to their age and health condition, such as jogging, brisk walking, and Taichi. Usually it′s safe if you can enforce "3, 5 ,7 " rules. "3" means to walk about 3kms each day, and time is up to 30 minutes; "5" means to take five times exercises each week; "7" means that you age plus heart rate after exercise is around 170. This kind of exercise is moderate and could help keep aerobic metabolism.

4.Reduce mental pressure and keep psychological balance

As longstanding mental pressure and depression is one of major reasons that lead to hypertension and other chronic disease. You could reduce pressure through many ways, such as consulting psychologist doctors, making friends and increasing social activities, developing sport or art hobby and so on.

5.Don′t smoke

It already has been proven that smoking is bad to health. In addition, smoking could reduce the compliance of taking medicines and increase the dose of hypotensor(medicines to reduce blood pressure)

Renal Vascular and Hypertension

Renal Vascular Hypertension means that stenosis of the trunk or branch of unilateral or bilateral renal artery cause renal blood lack and then lead to high blood pressure. It takes up 5% in total cases of hypertension. The causes of renal vascular hypertension are many and various, in the below are some common reasons.

1.Arteritis

It′s more common with Chinese people than with European or American people and it′s more common with young women. Arteritis is nonspecific inflammation and has connection with abnormal immunity after bacteria infection.

2.Atherosis

Renal vascular hypertension caused by atherosis occupys about 60% in the total number of patients in European and American countries. The diease occurs at the ostias of the trunk of renal artery or the position of 1/3 to it in most cases, and usually it′s bilateral.

3.Abnormal growth of fibrillar muscle

It′s the common cause to lead to renal vascular hypertension among foreign young patients.

4.Others

Such as polyarteritis nodosa, external injury, movable kidney, fibrosis of tissue arund renal artery caused by radioactive rays etc.

Top 5 Complications of Hypertensive Nephropathy

1.Anemia

Serious kidney damages make kidney unable in producing hemopoietin which is the essential substance for the generation of erythrocyte. Anemia is diagnosed when erythrocyte count is lower than the reference value.

2.Edema

Edema usually occurs as the first complication of Hypertensive Nephropathy. In serious cases, aside from a swollen body, patients may also experience hydrothorax and ascites which may bring patients hard breath, umbilical hernia and inguinal hernia.

3.Heart Failure

Heart failure usually occurs when Hypertensive Nephropathy progressive to kidney failure and it always occurs under the together action of high blood pressure, toxins in blood, renal anemia, acidosis and electrolyte disturbance.

4.Gastrointestinal Discomforts

Gastrointestinal discomfort is not the typical complication of Hypertensive Nephropathy and it may occur among people with any kind of kidney problem. Gastrointestinal discomforts include nausea, vomit, poor appetite and so on.

5.Cerebrovascular Accident

Cerebrovascular accident is one of the fatal complications of Hypertensive Nephropathy. With characteristics of rapid deterioration and high fatality rate, cerebrovascular disease can be the final case of patients′ death, so people with advanced Hypertensive Nephropathy should prevent it actively.

Hypertension Nephropathy is a the result of long-term high blood pressure and usually causes these complications when it develops to late stage, so early diagnosis and treatment is very essential for patients to prevent the above complications.

2014年1月26日星期日

Uremia and High Blood Pressure

As we all know, hypertension is one of the most common symptoms and complications of the disease of Polycystic Kidney Disease . And the worst prognosis of this disease is uremia. Many patients with this disease, however, don’t know that hypertension is one of the important factors for this disease to develop to uremia. So, what the patients should do to control the blood pressure and prevent uremia?

First, control the blood pressure on the ideal level

According to the general survey, more than half of patients with Polycystic Kidney Disease suffer from hypertension. Only less than 50 percent of patients, however, have realized they have hypertension. And among them, less than 12.5percent are taking medicine to treat the hypertension; and only 2.9percent of them can control the blood pressure in the ideal level. Therefore, we should spread the publicity of hypertension and it is extremely urgent to enhance the people′s cognition of the hazard of hypertension.

Second, take close examination of renal function

It is the precondition of preventing the damage of renal function to control the blood pressure in the ideal level. At the same time, we should take close examination of the renal function of the hypertension patients.

Third, choose therapeutic schedule and medicine reasonably

There are varieties of categories of antihypertensive drugs, which are suitable for different types of symptoms. The basic principle of choosing antihypertensive drugs is that the drugs do not contain the renal toxicity or even possess the function of renal protection. Research shows that ACEI, ARB, CCB, and βBRB can not only control the blood pressure but also can protect our kidney.

Preparation for Hemodialysis

When Chronic Kidney Disease develops to Stage IV along with GFR?30 cc/min, dialysis turn to an inevitable choice. Dialysis can be mainly divided into hemodialysis and peritoneal dialysis. The key of a successful hemodialysis depends upon awareness and preparation. So what should we do before we perform hemodialysis?

1.Certain tests should be taken before receiving hemodialysis

Those tests include heart check, vaccination status, dialysis access and some others. By detecting the heart condition in advance, the doctor could recommend you a better dialysis type; for example, those with diabetes or high blood pressure may have a weak heart than others, to those kinds of people, hemodialysis is their first choice.

2.Control your blood pressure

High blood pressure itself can damage kidney function. Taking good control of your blood pressure contributes to your kidneys especially during Chronic Kidney Failure or ESRD. Having a good control over your high blood pressure would effectively slow down the progression of Chronic Kidney Failure as well as reduce the incidence of cardiovascular complications. Besides, ultrafiltration and sodium discharge of dialysis have a confirming function of depressing high blood pressure.

3.Psychoneself

Doctor has the responsibility of helping patients get ready for hemodialysis. However, mental preparation in advance really matters, because it can not only help patients deal with the fact that he/she needs hemodialysis without delay, but also spare time getting down to vascular access.

4.Dialyser examination in advance is necessary

To check whether the package rupture or not, and whether dialyiser disrepair or not, instruction of the new dialyser should be read before usage. Realize about disinfection methods, material of membrane, pre-congestion amount, ultrafiltration rate, maximum tolerant pressure, clearance rate of small molecules and moderate molecular and remaining blood volume etc.

Uremia:Water and Dialysis

How much water to drink in dialysis? Water is the source of life, and under some occasions, water may become kind of poison. For uremia patients on dialysis, if they drink too much water under the state of oliguria or anuresis, it may cause acute heart failure and cause uremia heart diseases. The dehydration of dialysis patients is quick and big, and all these will increase the heart burden.

How much water is supposed to drink in dialysis? In order to control the water intake, the patients in dialysis should conduct healthy management: dialysis patients should check the weight everyday; it is normal to control the weight under a regulation around 5%. Patients with urine can properly loosen the control of water, but food rich in moisture content is not suggested. The dialysis patients can distribute the total water intake to different hours of a day.

Risk Factors that may Lead to Uremia

1.Chronic glomerulonephritis

For those patients who have been diagnosed with chronic glomerulonephritis, their kidney condition tends to aggravate at a higher rate if they have persistent proteinuria or their blood pressure is poorly controlled.

Also, the prognosis of the disease is also affected by the pathological classification and pathological stages. Some types of nephritis, such as MCD, light mesangial proliferation, would have good prognosis, while some types of nephritis, like mesangioproliferative glomerulonephritis, RPGN(rapidly progressive glomerulonephritis), would pose unfavorable prognosis. In some cases, patients would progress into uremia in a few months or weeks after the first attack.

2.Diabetic nephropathy

Once patients with diabetic nephropathy present clinical proteinuria, their kidney function would decline progressively. And almost one fourth of the patients with diabetic nephropathy would develop into uremia within six years once they present persistent proteinuria.

3.Hypertensive nephropathy

Patients with long-time medical history of hypertension and a poor control of their blood pressure would develop renal insufficiency apart from cardio-vascular diseases.

In addition, patients who had medical history of hypertensive crisis tend to develop damage to kidneys.

4.Bilateral hydronephrosis

Patients with bilateral hydronephrosis caused by kidney stones or other diseases would present bilateral hydronephrosis. If the obstruction could not lifted timely, kidney function would deteriorate in the long run, leading to uremia eventually.

5.Nephrotoxic medicines

Long-term intake of nephrotoxic medicines, such as certain antiobitics, pain-killers and chemotherapeutic drugs can also cause renal failure.

What is Hemolytic Uremia Syndrome

Hemolytic Uremia Syndrome mainly manifested as microangiopathic hemolysis, thrombocytopenia and acute renal failure; if accompanied with nervous system symptoms and noninfectious fever, it will be thrombotic thrombocytopenic purpura. Therefore, Hemolytic uremia syndrome and thrombotic thrombocytopenic purpura are similar in clinical manifestation and causes, and they both belong to thrombotic microangiopathy.

The causes of hemolytic uremia syndrome are still not very clear, and it may have relation with infection , inheritance and other factors. These factors lead to endothelial cells damage and broke negative charge brought by endothelial cells under physiology condition, decrease PGI2 and increase platelet adhesiveness; operated endothelial cells start blood clotting of white cells and plasma proteins, bring thrombopoiesis to happen, thus lots of blood cells are consumed and result in bleeding; hemolytic anemia will occur when red cells flow through vessels that is formed by microthrombus. Microembolization mostly occur in kidney, which may result in acute renal failure.

Why Uremia Patients Need to do Dialysis

Why do patients with kidney disease have to do Dialysis when enters into uremia stage?

Normally, kidney are the two “sewage treatment center” of human body, which are responsible for dispose of the wastes. Once kidneys have pathological changes and could not work as well, some of the wastes then could not be excreted out of the body and would build up. All of these wastes are the toxins that cause uremia, which’s life-threaten. The wastes can be divided into three major groups.

1.Small molecular toxins

These toxins’ relative molecular mass is below 500, which mainly include inorganic phosphorous, hydrogen ion, certain acid radicals, and urea, creatinine, uric acid, phenols and amines. Cyanate- metabolic product of urea- is neurotoxic. When creatinine reaches certain concentration, the life span of the cells would shorten, hemolysis would happen. Drowsiness and fatigue can also happen. Uric acid can cause gout. High-concentration polyamine can cause nausea, vomit and proteinuria, promotes the dissolution of red blood cells and restrain the production of EPO, resulting in anemia. Phenols can damage the nervous syImmunotherapy. Either excessive concentration of potassium ion or hydrogen ion can be life-threatening.

2.Middle molecular toxins

These toxins’ relative molecular mass is between 500 and 1000, which mainly are some peptides, which can cause peripheral nervous lesions, abnormal glucose tolerance, and also restrain the cell production, phagocytic activity of leucocytes, the growth of lymphocytes and fibrocytes.

3.Large molecular toxins

These toxins’ relative molecular mass is more than 1000, mainly containing some hormones, such as growth hormones, parathyroid hormone, corticotrophin, gastrin, insulin, which can cause central nervous syImmunotherapy dysfunction, calcification or necrosis of soft tissue, bone disease, pruritus, hyperlipemia, anemia, erectile dysfunction and secondary hyperthyroidism.

As listed, all of these toxins would lead to serious consequences if they are building up in the body. So the major task of the treatment of uremia is to get rid of the toxins. Dialysis, whether it is hemodialysis or peritoneal dialysis, can help clear the small and middle molecular toxins out of the body. So the kidney patients can sustain their lives.

What is Uremia

Uremia is a condition in which the body is unable to remove metabolic wastes and toxins from blood to maintain water, electrolyte, acid-base balance. Uremia usually refers to the severe renal failure. In the end-stage renal failure, GFR is less than 15. In most cases, damage many systems of the body.

Cardiovascular diseases:

Damaged kidneys lead to water retention or edema. High blood pressure is aggravated in end-stage renal failure. Also a sudden rise in potassium can increases the risk of cardiovascular disease. Retention, aggravated high blood pressure and rise of potassium increases the risk of cardiovascular diseases attack.

Respiratory diseases:

Short of breath is a symptom of respiratory disease. Pulmonary edema is very dangerous which may lead to death.

Sensory Effects:

Peripheral neuropathy may happen to patients with uremia that usually are in upper extremities. The manifestations of sensory problems include weakness and dizziness. Cerebral edema may cause metal confusion.

Sexual diseases:

Estrogen production and testosterones is reduced duet to effects of uremia toxins. Man with uremia may experience ED and has no desire of sexual life.

Metabolic System:

Impaired kidneys are unable to excrete medications or waste products. Medications and chemotherapy may cause severe toxicity problems. The kidneys are unable to maintain electrolyte balance.

Kidney Insufficiency and Uremia

Does renal insufficiency mean uremia?

Some people are confused about this question. Those who’re newly diagnosed with renal insufficiency may be scared and wonder.

In the clinical, chronic kidney disease can be divided into four stages. The four stages are compensation stage of renal insufficiency, discompensation stage of renal insufficiency, early stage of renal failure and advanced stage of renal failure (uremia).

In the compensation stage of renal insufficiency, chronic kidney disease patients can not feel any symptoms, and their creatinine level, GFR are all in normal range because of the compensation ability of the kidney. As we know, one important function of kidney is filtration. When some renal glomeruli are damaged and fail to work, the other healthy renal glomeruli will do more work to replace them. So creatinine and other toxins such as blood urea nitrogen, urea acid can be cleaned out of the body. In this stage, chronic kidney disease patients even do not have to limit the food which they take in. They do not have to limit water and keep low salt for the discharge of water is also normal.

In the discompensation stage of renal insufficiency, other renal glomeruli which do more work will also be tired and fail to work for a long time. In this stage, level of serum creatinine, blood urea nitrogen and urea acid may increase a little and chronic kidney disease patients can have symptoms such as anemia, fatigue, decreased body weight, and can not concentrate, and so on. These are usually ignored. If suffering from loosing water, infection, bleeding and so on, obvious symptoms will appear soon.

The third stage is early stage of renal failure. In this stage, renal function declines seriously. Chronic kidney disease patients in this stage can easily feel fatigue, weakness. Besides, anemia will become more obvious. Urine at night will also increase. In addition, blood urea nitrogen and serum creatinine also increase obviously. Acidosis can also be accompanied. So this stage can also be called azotemia stage.

The last stage is advanced stage of renal insufficiency(uremia). In this stage, chronic kidney disease patients have serious symptoms in clinic such as severe nausea, vomiting, little urine, edema, high blood pressure, serious anemia, itch in skin, and so on.

Will Uremia Cause Nosebleed

Uremia is an end stage of various kidney diseases and it is a kind of serious kidney disease. With the development of kidney disease, it will gradually involve other organs of human body. In the early stage, digestive tract symptom will appear, the patients will have symptoms such as nausea, vomiting, poor appetite and etc. In the later stage, symptoms such as heart failure, coma, insanity will gradually appear. If these symptoms are not treated timely, it will threaten the life of the patients. Nosebleed is also a symptom of uremia; it is often caused by nasal mucosa rupture or high creatinine. The best method to solve this is to receive efficient uremia treatment and control all the complications before they emerge.

Traditional Chinese Treatment is an efficient way to treat uremia. The Hot Compress Therapy of Huaxia Kidney Disease Hospital is one branch of Traditional Chinese Treatment. It uses traditional Chinese medicine to treat kidney disease in an iontophoresis way. From the time it founded, it has helped over one hundred thousand people get ride of kidney disease and live a normal life again. We would also like to help out of the suffering of kidney disease.

How Long Can I Live with Uremia

How many years can patients with uremia survive? There is no definite answer for this question. The life expectancy of patients with uremia is related to the body condition of the patients, the serious level of the disease, the treatment that they are receiving, the diet and nursing condition. For those patients who receive dialysis as the only way to treat uremia, the longer they receive dialysis, the more frequent they will go to hospital. For long time of dialysis will make the patients rely on it and also result in the protein loss and anemia. Once the patients stop dialysis, they will put their life at risk. Therefore, dialysis only is not a good choice for patients. Doctor in Huaxia kidney Disease Hospital suggests that the patients can receive dialysis and traditional Chinese Treatment at the same time. On one hand, dialysis will make the patients feel better and avoid complications for a while; on the other hand, traditional Chinese Treatment can treat uremia from the root and gradually prevent kidney damage and protect the remaining kidney units.

What Kind of Kidney Disease will Progress into Uremia

1.Chronic Glomerulonephritis

For those patients who have been diagnosed with chronic glomerulonephritis, their kidney condition tends to aggravate at a higher rate if they have persistent proteinuria or their blood pressure is poorly controlled.

Also, the prognosis of the disease is also affected by the pathological classification and pathological stages.

2.Diabetic Nephropathy

Once patients with diabetic nephropathy present clinical proteinuria, their kidney function would decline progressively. And almost one fourth of the patients with diabetic nephropathy would develop into uremia within six years once they present persistent proteinuria.

3.Hypertensive Nephropathy

Patients with long-time medical history of hypertension and a poor control of their blood pressure would develop renal insufficiency apart from cardio-vascular diseases.

What Should Uremia Patients Pay Attention to After Hemodialysis

What should uremia patients pay attention to after hemodialysis? How to nurse for uremia patients after hemodialysis? Hemodialysis helps the patients to excrete the toxins inside the body instead of the kidney function. Hemodialysis patients need monitor their weight and urine output every day. Daily water inflow should be the urine quantity adding 500 ml water. Here, water means all of the foods containing. Porridge and noodles contain a lot of water, which the patients should be limited.

What should uremia patients pay attention to after hemodialysis? In daily life, uremia patients should not take heavy things and wear too tight clothes or bandage too tight. They should keep clean and prevent infection.

What Can Not Eat If I Have Uremia

For uremia patients in the usual treatment, in addition to the conventional therapy, the patients should pay much attention to the diet. From Traditional Chinese Medicine, diet plays an important role in the disease treatment.

Which foods can not uremia patients eat? Generally speaking, the diet principle of uremia patients is that they should limit proteinuria, sodium, potassium and water, and supplement enough calories. The details as the following:

Patients with edema and less quantity of uremia should avoid salt, potassium, too salty foods, high potassium foods (such as kelp, laver, mushrooms, potatoes, etc. ), high uric acid food (such as animal innards, dry seafood, fish, beans, etc.), acrimony and stimulating foods (such as pepper, Chinese prickly ash, coffee, wine, etc.); Avoid greasy foods. Besides, the patients should not eat some fruit, such as banana, grapefruit, orange, melon, etc.

How to Treat Uremia Without Dialysis

Uremia is the end stage of kidney disease. Renal failure is irreversible and generally it is difficult to be cured. However, we can use some conservative treatments to slow down the kidney disease changes, maintain normal physiological function of patients and help them reduce the number of dialysis.

Can uremia be cured? What are the symptoms of patients at the end stage of uremia? The symptoms of the nervous system is the main symptom of uremia. At the early stage of uremia, patients often have some symptoms, such as dizziness, headache, fatigue, comprehension and memory loss, etc. With the deterioration of the disease, the symptoms, such as dysphoria, muscle tremor and convulsions may appear. For uremia patients, the earliest symptom of digestive system is a loss of appetite and indigestion. With the disease aggravating, anorexia, nausea, vomiting and diarrhea may occur. Due to the function of renal hypertension, acidosis, hyperkalemia, sodium and water retention, anemia and toxic substances, chronic renal failure patients may suffer from heart failure, arrhythmia and myocardial damage, etc. Itchy skin is a common symptom in uremic patients, patients′ skin is dry, desquamation and golden brown.

Can uremia be cured? Generally speaking, at the end stage of uremia, your doctor will recommend you dialysis. Dialysis replaces the function of kidney and discharge the toxin inside body and maintain the normal function of the human body. But, dialysis is not a treatment. It just exercises an artificial kidney function. Kidney transplant is a choice of patients with end stage of uremia. Through the kidney transplant, the patients can prolong their life. But, it is expensive. And, later, the patients need to take large quantity of medicine to eliminate the rejection. Besides, the patients can adopt The Hot Compress Therapy of Huaxia Kidney Disease Hospital to relieve the disease process.

Uremia Basics:Causes and Symtpoms

Causes of Uremia

1. Various kidney diseases account for the main cause.

2. Infection of urinary system or urinary tract infection.

3. Toxic side effects of some medications.

4. Approximately 30% of patients with Diabetes Mellitus may develop Uremia.

5. Uremia cases caused by HIV infection is in rising trend.

6. About 15% of high blood pressure will become Uremia.

Symptoms of Uremia

For uremia patients, the symptoms may include excessive thirst and reduced urination, nausea and vomiting, a drying mouth, swelling (edema of the entire body, hands, feet and face, etc.), abdominal pain, Confusion due to reduced mental alertness, pale color of the skin, tiredness, fatigue and increased irritability, increased pulse rate, tremors and seizures, fever and a low blood pressure, nocturnal urination, Anorexia and weight loss, inexplicable small bruise and pericarditis.

Uremia Tips:How to Prevent Uremia

Uremia is not an independent disease while it is a clinical syndrome owned by various end-stage kidney diseases and the end stage of chronic kidney failure. In this stage, the kidney is seriously damaged and can not maintain the body′s metabolism and water electrolyte and acid-base balance, so that endocrine dysfunction causing a series of poisoning symptoms in the body. However, please don not worry. As long as the patients can diagnose and accept the effective treatment, uremia can be prevented.

1. When kidney disease is early detected, the patients do not delay the time and go to see a doctor at once. If delayed, the disease may become chronic disease and eventually develop into uremia.

2. In daily life, we should study more kidney disease knowledge. Generally speaking, the early symptoms of kidney disease may occur in urine changes, such as having proteinuria.

3. The patients with high blood pressure and diabetes should control their blood pressure and blood sugar actively and make them keep normal.

4. In daily life, people do not eat drugs casually, such as painkillers, which will cause damage to your kidney.

According to The Hot Compress Therapy of Huaxia Kidney Disease Hospital, once people suffer from kidney disease, besides accepting the traditional treatment, the patients shoul pay attention to their diet, sleep, nutrition and mood.

What are the differences between Nephritis and Uremia

Chronic nephritis is the early stage of uremia. If chronic nephritis can not be treated reasonably, it will progress into renal failure and even uremia at last. Then, what are the difference between nephritis and uremia?

According to the original causes, nephritis can be divided into primary glomerulonephritis and secondary glomerulonephritis. According to the time, nephritis is divided into acute glomerulonephritis and chronic nephritis, also known as chronic glomerulonephritis. Acute nephritis, chronic nephritis, nephrotic syndrome and iga glomerulonephritis belong to primary nephritis; secondary glomerulonephritis includes purpura nephritis, lupus nephritis, diabetic nephropathy and hypertensive nephropathy.

Uremia is caused by renal failure. And the causes of renal failure are various reasons forming into nephritis, such as acute glomerulonephritis, interstitial nephritis, diabetic nephropathy, polycystic kidney disease and severe high blood pressure. Severe hypertension can cause renal arteriolar sclerosis, renal blood flow reduction, renal function damage, lower urinary tract obstruction.

Because renal corpuscle is damaged, the kidneys of nephritis patients suffer from edema, high blood pressure and proteinuria. Nephritis is the most common disease among kidney diseases.

Uremia actually refers to the human body not be able to produce urine through the kidneys, the metabolic waste and excess moisture can not be excreted from the body, which causes poisoning.

Nephritis and uremia are two different things. But they can be said to the two different stages of a disease. Nephritis can not surely develop into uremia. Most nephritis patients can be cured after effective treatment .

What Are the Symptoms of Uremia

Uremia is not an independent disease, but a common clinical syndrome of various kidney diseases developing into the late stage. For uremia patients, they should know about the symptoms of uremia. Then, what are the symptoms of uremia?

Slight fatigue, distraction;

Stomach upset, nausea, vomiting, gastrointestinal bleeding;

Nocturia, polyuria, urine color light;

Anemia and pale face;

Easy bleeding;

The whole body bone pain or back pain;

Irregular menstruation;

Decreased sexual function;

Cramps frequently.

The Worst Foods for a Uremia Patients

1. Gluten products: gluten, flour sausage, baked bran.

2. Beans and bean products forbidden foods: soybean, soybean, mung beans, red beans, peas, tofu, bean curd, soya-bean milk.

3. Dried fruit and candied fruit: seeds, peanut, walnut, cashew, chestnut, raisins, dried peach, dried apricot and dried persimmons.

4. Milk: ice cream and more than two cups of milk.

5. Vegetables: kelp, laver, pickles, pickled vegetables, pickles. These vegetables are forbidden foods for uremia patients.

6. Salty or smoked meats: such as salted fish, bacon, bacon, duck, ham, sausage, salted and preserved eggs, sardines, canned meat, brain, etc.

7. Seafood: shrimp, crab, clams, mussels and oysters.

8. Staple food: salty bread, crackers.

9. Fats and oils: butter, margarine.

How to Relieve Ammonia Odor in Uremia Patients

1.Why Uremia causes ammonia odor?

In Uremia, ammonia odor is associated with high levels of blood urea nitrogen(BUN) in bloodstream. Blood urea nitrogen, a wasteful product of proteins, is normally removed by the kidneys. When the kidneys are not functioning well, blood urea nitrogen will accumulate in the body. The excess urea will be decomposed into ammonia under the effect of urea enzymes in gastrointestinal tract. Ammonia will be discharged through oral cavity to cause the bad odor. In addition, high BUN in saliva can also be decomposed into ammonia to make the symptom even worse. BUN running through pulmonary circulation to be discharged through respiration also contributes to the symptom.

2.How to relieve ammonia odor in Uremia?

Controlling your intake of proteins as prescribed by doctors and dietitians based on your condition is essential for controlling high BUN in blood and stopping the symptom from getting worse. At the meantime, start to make some small changes for oral health to make the symptom better. Rinse your mouth with a solution of one cup of water and one teaspoon of salt; after rising, spit out the solution. In addition, brush or scrape your tongue with a tongue cleaner. Because your tongue is directly posed to ammonia, scraping the layers will reduce or eliminate the symptom. As for reduction of high blood urea nitrogen, traditional Chinese medicine treatment may be a better option. Chinese herbs have known functions including expanding blood vessels, reducing blood stasis and accelerating blood circulation, so it may help to discharge elevated toxins and reduce ammonia odor.

2014年1月25日星期六

What Causes Nephrotic Syndrome in People

Many Nephrotic Syndrome patients are confused why they are diagnosed with Nephrotic Syndrome, because they think they are healthy and there is no possibility for them to get Nephrotic Syndrome.

Then what causes Nephrotic Syndrome? Some explanations are as follows.

First, we should know what is Renal Glomeruli. Glomeruli refers to tiny blood vessels that filter wastes and excess water from the blood and send them to the bladder as urine. When damages caused on Kidneys’ glomeruli, Nephrotic Syndrome will occur.

When the glomeruli are working properly, they keep protein in the blood from leaking into the urine. Healthy kidneys allow less than 1 gram of protein to escape through the urine in a day. In nephrotic syndrome, the damaged glomeruli allow 3 grams or more of protein to leak into the urine during a 24-hour period.

As the result of this, protein loss, the blood is deficient. Normal amounts of blood protein are needed to help regulate fluid throughout the body. Protein acts like a sponge to soak up fluid into the bloodstream. When blood is low in protein, fluid accumulates in the body’s tissues rather than circulating. The fluid causes swelling and puffiness.

Nephrotic syndrome can occur with many diseases. In adults, the most common causes are diabetic nephropathy and membranous nephropathy. In older adults, the most common cause is amyloidosis. Prevention of nephrotic syndrome relies on controlling these diseases. However, the cause of nephrotic syndrome is unknown.

What are the symptoms of Nephrotic Syndrome

When symptoms are present, they can include as follows:

1. Patients always feel very tired, loss of appetite, pale and dispirited;

2. The blood pressure of most of the patients is normal, few patients have high blood pressure;

3. Shortness of breath caused by fluid buildup in the lungs. Adults older than 65 may be misdiagnosed with heart failure, Children are often thought to have allergies.

4. Swelling in the tissues around the eyes or in the feet or ankles .This is the most common early symptom of nephrotic syndrome in both children and adults.

5. Less urine: The urine is often less than 400ml per day or even anuresis.

What are the Complications of Nephrotic Syndrome

1.Infection

A large number of immune globulin from urine loss, plasma protein reduced, affecting antibody formation. Adrenal cortex hormones and the application of cytotoxic drugs, in which patients resistant to systemic decline in vulnerable to infection, such as skin infections, primary peritonitis, respiratory tract infections, urinary tract infection, or even induced sepsis.

2.Thrombosis

thrombosis prone patients with nephrotic syndrome, particularly in the incidence of membranous nephropathy up to 25% ~ 40%. The reasons for the formation of thrombus edema, the patient′s less venous stasis, high blood lipids, blood concentration to viscosity increase, high fibrinogen levels, and v, Ⅶ, Ⅷ, x factor increases and the use of adrenal cortex hormones and the blood-prone hypercoagulable state and so on.

3.Coronary heart disease

nephrotic syndrome patients often have hyperlipidemia and hypercoagulability, so prone to coronary heart disease. It was reported that patients with nephrotic syndrome, the incidence of myocardial infarction 8 times higher than normal. Nephrotic syndrome with coronary heart disease has become the cause of death of the third factor (after infection and renal failure).

4.Acute renal failure

patients with nephrotic syndrome due to massive proteinuria, hypoalbuminemia, hyperlipidemia, often in a low blood volume and in vivo hypercoagulability. District vomiting, diarrhea, use of antihypertensive drugs and , when a large number of diuretic diuretic, may make a sudden decrease in renal blood perfusion and thus make lower glomerular filtration rate, leading to acute renal failure. In addition, nephrotic syndrome and renal interstitial edema, and protein concentration blocked the formation of tubular casts and other factors can also be induced acute renal failure.

5.Electrolyte and metabolic disorders

repeated use of diuretics or long-term ban on unreasonable salt can enable patients with nephrotic syndrome secondary to hyponatremia; the use of adrenal cortex hormones and a large number of diuretics result in a large number of urination, if not timely fill potassium, prone to hypokalemia.

How to Treat Nephrotic Syndrome

1.Control proteinuria actively

For Nephrotic Syndrome patients, they experience edema symptom due to severe protein leakage. And usually, the more protein in urine, the more severe the edema. Therefore, controlling proteinuria is also an important part in treating edema associated with Nephrotic Syndrome.

2.Limit fluid intake, so as to avoid worsening illness condition

For an individual with edema, he needs to reduce fluid intake, as drinking too much water will increase kidney burden and worsen illness condition. Generally, patients can drink 500 milliliter more fluid than the volume of their urine output. Besides, for kidney failure patients, if they have started dialysis, they may need to follow different principles about fluid intake.

3.Diuretic

If left uncontrolled, fluid retention may spread to lung, causing pulmonary edema which can cause shortness of breath. Diuretic can be used to help our body discharge excess fluid, but the one thing that should be kept in mind and that is what kind of diuretic can be used should depend on patients’ potassium level. In clinic, there are different kinds of diuretics. Some of them can help to discharge excess potassium and some of them can protect potassium from being discharged out of the body.

4.Improve kidney function

Kidney is a bean-shaped organ with filtration function. While filtering blood, excess fluid will be discharged and nutrition are kept in the body. For Nephrotic Syndrome patients, kidneys are damaged and can not function properly, which lead to large amounts of protein leak from urine and excess fluid stay in the body. Therefore, improving kidney function is the key point for Nephrotic Syndrome patients to get edema treated effectively.

What are the Causes of Nephrotic Syndrome

For people with Nephrotic Syndrome, they release massive protein in urine and form proteinuria. Proteinuria is the dominant symptom of Nephrotic Syndrome and it can cause edema, hypoalbuminemia and hyperlipidemia directly.

Protein is the essential nutrition of our body and can be divided into different types. Kidneys are responsible for filtering blood and when protein flow into kidney with blood, glomerular filtration membrane perform function to protect them from being leaked. Therefore, in normal cases, no protein be detected out in urine.

However, for people with Nephrotic Syndrome, their filtration membrane is damaged and protein can pass through casually. When protein flow through membrane and flow out of our body with urine, proteinuria is formed. Without timely and effective control, more and more protein leak out, as a result of which, protein content in blood decreases. Hypoalbuminemia refers to the illness condition where levels of albumin in blood serum are abnormally low.

Besides, because of great loss of protein in urine, plasma osmotic pressure decreases. Under such a conditon, fluid in blood ooze and into surrounding tissues. Edema is caused when there is an abnormal accumulation of fluid in the interstitium.

Hyperlipidemia means high lipid level in blood and it also can be caused by serious loss of protein from urine. We know protein is the irreplaceable nutrition of our body. When large amounts of protein are lost from urine, our liver will produce some protein to meet our physical demand. When liver synthetizes protein, lipid is produced at the same time. For Nephrotic Syndrome patients, because of severe shortage of protein, their liver has to work continuously to produce protein. When this condition lasts for a long time, lipid content in blood increases and hyperlipidemia is caused.

Why Nephrotic Syndrome Have Vomit

There is a variety of diseases and conditions which can contribute to vomiting in nephrotic syndrome.The detailed causes will be explained as follows.

Edema

Edema is one of typical signs of nephrotic syndrome. In serious case,fluid can build up in gastrointestinal tract. It also can make the patients with nephrotic syndrome vomit.

Waste products

As renal function declines, metabolic waste products and toxins can not be eliminated from body adequately. The waste products in intestinal tract can irritate mucosa, thus giving rise to vomiting in nephrotic syndrome.

Electrolyte imbalance

One of important kidney functions is to keep the balance of different types of minerals in body by removing extra minerals like sodium,potassium etc from body. However, if the kidneys are impaired, they fail to balance the electrolyte balance. Electrolyte imbalance can cause vomiting in nephrotic syndrome.

Side effects of some medications

A number types of medications will be prescribed to treat nephrotic syndrome. Steroids and immunosuppressive drugs are the most commonly used medications for the disease.Vomiting can be a side effect of certain kinds of medications.

Exercises and Healthy Lifestyle for Nephrotic Syndrome Patients

Proper health cares are very important for nephrotic syndrome patients. After years’ clinical treatment, nephrologists suggest that regular and proper excises are very conducive and beneficial.

Nephrotic syndrome patients have varying degrees’ heart failure and it will be more serious of complicated with hypertension and anemia. One good way to control blood pressure is persistent proper exercises which can help patients lose weight and improve the heart functions. What is more, anemia can also be improved through exercises which can help increase the function of hemoglobin.

For those that have been taking long time dialysis, the lack of active vitamin D will cause renal osteopathy. The vitamin D in the foods can not be used by the body because the enzyme for transforming into active vitamin D is inhibited. The supplement of active vitamin agent has the risk of causing hypercalcemia. Therefore it is a good choice to take outdoor sports and sunbath which can help form natural active vitamin D through photochemical synthesis and lower the incidence of renal osteopathy.

It is common that nephrotic syndrome patients will have skin itching especially among elderly people. To prevent itchy skin, patients can take proper exercises besides thorough dialysis, proper bath and avoidance of certain excitant foods. Sweating after exercises with skin massage can help excrete toxins and promote blood circulation.

Then what are the exercises that are suitable for them? Proper exercises are conducive for them, but they should avoid strenuous exercises or over-tiredness. Mild and relaxed exercises such as walking, tai chi and qi gong are all good choices, which can help alleviate the symptoms, build up physical strength, reduce the incidence of catching cold, protect renal functions and reduce the risk of osteoporosis.

How to Prevent Nephrotic Syndrome in Children Developing Chronic Kidney Disease(CKD)

Both adults and children can have Nephrotic Syndrome. Nephrotic Syndrome in children can occur at any age but is most common between the ages of 1? and 5 years.

Proteinuria is a very common symptom of Nephrotic Syndrome in children, and it affects the prognosis of condition to a large extent. The condition most commonly associated with Nephrotic Syndrome in children is minimal change disease which in general has a good prognosis. However, other types of Nephrotic Syndrome may not have that good prognosis, like FSGS, MPGN. Once patients do not respond to the steroid drugs and even immunosuppressive agents well, it will put them at risk of developing adult chronic kidney disease after years with the gradual decrease in GFR level and loss of renal function.

Then, how to prevent Nephrotic Syndrome in Children developing adult chronic kidney disease? The best way is to increase GFR level and recover renal Function. Once Nephrotic Syndrome in Children can not be controlled well by the current treatment, maybe The Hot Compress Therapy of Huaxia Kidney Disease Hospital can become patients’ better choice. This treatment is based on Chinese herbal medicines, but used externally. Besides, this therapy is an overall treatment, which is not only a simple therapy, but also related to other sides of patients’ living, including medicine, nursing, psychology, emotion, nutrition, diet, exercise, rehabilitation and etc.

High Quality Protein Diet for Chronic Kidney Failure

Diet plays an important role in the treatment of chronic renal failure. Therefore, chronic renal failure patients should pay much attention to their diet in daily life. Especially, the patients should pay attention to low protein diet.

The patients should injest high quality protein with high nutritional value; that is to say, the protein intake should be fewer and better. Controlling the protein intake can block or slow down the process of chronic renal failure. High quality protein contains a large amount of essential amino acids, which will produce less nitrogenous substances after decomposition in the body. These proteins are represented by animal protein, such as chicken, fish, milk, lean, etc. Vegetable protein generally contains more non-essential chloride acid, which has low biological titer and after eaten, it can produce more nitrogenous substances; therefore, the patients should limit its intake. Especially some stable foods with high vegetable protein, such as corn, wheat flour, and dry beans, soy products, nuts, etc. , the patients with worsening renal function should more strictly control intake.

How to Delay Nephritis from Developing into Renal Failure

For nephritis patients, various infections can lead to the body′s antibodies rising, the antibodies will destroy the basement membrane of kidney, and eventually cause further damage of kidney function. In order to delay nephritis patients’ renal failure, our experts give you some suggestions as follows:

In daily life, the patients should pay attention to appropriately keeping warm, especially preventing colds and diarrhea, which are the common infections. Colds and diarrhea easily aggravate the renal function damage. Besides, the patients do not do a lot of movement and should rest properly because a lot of movement may make the patients suffer from heart failure.

About diet, kidney disease patients should control the quantity. For uremia patients, eating too much may cause overnutrition; the waste can not be excreted from the body and then enter into the blood, which will aggravate renal failure.

How to Prevent Renal Failure

1. Enhanced physique:

The main measures of preventing kidney disease is to strengthen physical exercise and strengthen the body′s resistance to disease.

There are many means of physical exercise, such as walking, running, dancing, mountain climbing, boating, wushu, qigong, tai chi, etc., which are all beneficial to strengthen physique, improve the body resistance and prevent bacteria infection.

2. Prevent infection:

The occurrence of nephritis is often associated with upper respiratory tract infection.

3. Regular life:

Developing good habits is very important for good health. Because not regular life and not enough sleep, eat and drink too much, debauchery, overwork can reduce the body′s resistance and increase the chances of the disease.

4. Treat diseases early:

furuncle and prurigo of skin, upper respiratory tract infection, and repeated tonsillitis may cause nephritis.

5. Keep optimistic mood.

6. Carefully using the renal toxic drugs:

Aminoglycoside antibiotics such as gentamycin, kanamycin, streptomycin, amikacin, polymyxin B, tetracycline, vancomycin, amphotericin B and first element 2 are all have certain renal toxicity, or are easy to cause kidney damage; therefore, the patients had better not use them.

What are the Common diseases Causing Chronic Kidney Failure

There are various common diseases causing chronic renal failure, here, we will introduce them to you in detail.

The primary basic diseases mainly include chronic nephritis, a part of primary nephrotic syndrome, IgA nephropathy, chronic interstitial nephritis, hereditary nephritis, polycystic kidney disease, etc.

Secondary basic diseases mainly include diabetes, high blood pressure, hyperuricemia, systemic lupus erythematosus (sle), allergic purpura, renal amyloidosis, multiple myeloma, primary systemic vasculitis, etc.

In addition, infectious diseases such as chronic pyelonephritis, hepatitis b or hepatitis c virus (HCV) infection; obstructive diseases such as kidney stones, hyperplasia of prostate hypertrophy, prostate cancer, etc. Other diseases such as malignant tumor, drug poisoning, etc.

In the above primary diseases, chronic nephritis and tubular interstitial nephritis are the most common; in the above secondary diseases, diabetic nephropathy and high blood pressure are the most common.

Can High Creatinine Causes Kidney Failure

Creatinine level is used to measure kidney function, so patients always doubt whether high creatinine leve will lead to renal failure. In fact, creatinine level can indicate kidney problems in many cases, but it does not mean high creatinine level will always lead to renal failure.

Will high creatinine lead to renal failure?

Kidney failure indicates the kidney has almost lost its ability of filtering blood and discharging wastes. Creatinine is the metabolin of creatine and in a normal case it can be discharged by healthy kidneys. Therefore, creatinine level is usually in a stable range. Once you are diagnosed with chronic kidney disease, your kidneys can not work effectively and timely to discharge excessive creatinine. In this case, serum creatinine level increases. When a small part of your kidney function is damaged, creatinine level has no obvious increase, as the other part of your kidney function can also remove excessive creatinine out of your body. The medical research shows that creatinine level increases when your kidneys lose half of their function. In this case, high creatinine level means that your kidneys have been severely damaged.

Do you need to worry too much about temporary high creatinine?

People will sometimes have high creatinine level. This may be caused by many reasons. For example, before their tests, they eat much meat, do strenuous physical exercise or have improper diet, which can also lead to slightly high creatinine level. However, this high creatinine level is only temporary and after some time, it will be normal. Temporary high creatinine level does not lead to renal failure. What you should do is to regulate your daily diet and do exercise moderately, which will make your creatinine level in a stable range, and you need not worry too much about it.

Creatinine is just one of measurement of reflecting kidney function and does not mean high creatinine level will always lead to renal failure.

Why Renal Failure Have Skin Itching

Why Renal Failure Have Skin Itching
Skin itching is one major symptom and discomfort among kidney failure patients especially those that are on dialysis. Other more common problems caused by kidney failure include sleep problem, depression, bone problems, restless leg syndrome.

Skin itching can be caused by a variety of factors.

Dialysis

Dialysis can cause a series of complications and side effects and one of them is itching skin. This is because dialysis can cause the skin to produce less oil. Creams and some oil-based products can help in this case. Another reason is release of histamine due to allergies that dialysis patients might experience.

Dry skin

For end stage renal disease patients, their kidneys fail to clear metabolic wastes and excessive minerals such as calcium and phosphorus in the blood. As a result, the body will naturally remove liquid in the skin to the bloodstream to cope with too high mineral level. Skin dehydration will cause itching feeling which can be alleviated after being moisturized or rehydrated.

Histamine release

Histamine is a kind of protein which will be released by the body when there is foreign materials invading the body. The skin might feel itching as an allergic reactions to histamine release. On the other hand, histamine can cause less fluid in the blood vessels and this will worsen skin dehydration. In this cases, anti-histamine medicines might help achieve instant relief.

Alternative Treatment for Kidney Failure Without Dialysis

Dialysis is required by kidney failure patients, as failed kidneys can not purify blood and there are high levels of toxins in blood. Dialysis helps to clear these toxins away from blood, which is essential for protecting other internal organs.

However, dialysis has some side effects, such as making the patients losing their renal function, heart failure, hypotension, muscle spasm and cardiac arrhythmia, etc.

For an individual with kidney failure, dead kidney tissues can not be brought back to life, so their injured kidneys can not be cured, but with efforts, it is quite possible to get impaired kidney function improved. We know toxins pile up in blood, as kidney function is affected, so as long as kidney function is strengthened effectively, much more toxins will be discharged successfully and timely. Also, dialysis is avoided or delayed.

The Hot Compress Therapy of Huaxia Kidney Disease Hospital is a herbal treatment that can be used to treat kidney failure. It helps to improve kidney function and causes no discomforts during the whole treatment process. Although it is helpful, but it is only available for these who still have a certain urine output and kidney function. Therefore, if you meets this condition, The Hot Compress Therapy of Huaxia Kidney Disease Hospital will be a good choice for you to improve kidney condition. What’s more, this therapy nearly has no side effects.

Can Chronic Kidney Disease Causes Kidney Failure

Kidney failure is the end stage of various chronic kidney diseases in which part of or all kidney functions have been lost. Since CKD is a group of chronically progressive diseases, the final renal failure is actually can be prevented if it can be detected in the early stage and effective treatments are received timely.

Therefore we need to know what the early signs of CKD are. Before having obvious clinical symptoms, many CKD patients have already experiencing long term asymptomatic stage and it is not easy to be diagnosed without related tests and examinations. However there are indeed some early sign and only it requires enough attention and importance. For example, back pain, edema, high blood pressure, anemia, bubble urine, reddish urine, etc. Most people do not pay enough attention to these symptoms and just ignore them; actually they are warnings from the kidneys. If young people have increased night urination, it might be the early symptom of renal hypofunction and should arouse enough attention.

The routine physical examination is the best method for early detection of kidney disease and regular urine test can make a preliminary diagnosis. If there are proteinuria and hematuria, early treatments should be taken to prevent further aggravation and protect remaining kidney functions.

Proper early preventions are also of great importance, it mainly consists of the following aspects:

1. Positive and timely treating primary disease including glomerulonephritis, lupus nephritis, purpura nephritis as well as diabetes and hypertension so as to prevent chronic renal failure.

2. Prevent or eliminate risk factors for aggravating renal functions including renal toxic drugs, severe infections, dehydration, urinary obstruction, traumas, etc.

3. The application of ACEI can not only control high blood pressure but also rectify the renal states of high perfusion and high filtration so as to slow down the progression into renal failure.

Reasonable diets. It has been proved that low-protein, low-phosphorus and low-fat diets can help protect kidney functions for chronic kidney disease patients.

How to avoid Kidney failure with Iga Nephropathy

IgA Nephropathy is an autoimmune disease and onset of it is closely related with immune system. Similar with other kinds of kidney problem, IgA Nephropathy also cause kidney failure if not treated well. Then, how to prevent kidney failure with IgA Nephropathy?

Most of the times, IgA Nephropathy patients are prescribed with immunosuppressive agents to block inflammation, so as to prevent further kidney damages. This is very helpful and illness condition can be brought under control effectively. However, this can not solve problem permanently and when patients stop taking medicines or reduce dose of medicine, illness relapses. In IgA Nephropathy cases, we know inflammation occurs due to IgA deposition in mesangial area, so only when these deposition are removed effectively, can inflammation be prevented and further kidney damages be avoided radically.

The Hot Compress Therapy of Huaxia Kidney Disease Hospital is a recommended treatment for IgA Nephropathy patients. It helps to extend blood vessels, block inflammation, prevent coagulation and degrade extracellular matrixes, which is very essential for protect residual kidney tissues and remove IgA deposition. As long as IgA deposition are cleared away from kidney, further kidney damages are avoided and kidney failure is prevented effectively.

Will Dehydration Lead to Kidney Failure

Will Dehydration Lead to Kidney Failure
Dehydration refers to an abnormal physical condition and means the body does not have as much fluid and water as it should. With dehydration, we may experience various discomforts like joint pain, dyspeptic pain, constipation, asthma and even allergies and so on.

How does dehydration cause renal failure?

Dehydration can cause renal failure. We know kidney is the organ that takes charge of filtering blood. During this process, wastes produced in the body and excess fluid can be discharged out of the body with urine. For one with dehydration, his body can not adequately circulate blood and the wastes that it carries. Consequently, waste products like creatinine and urea nitrogen accumulate in the body. Dehydration can cause renal failure, but this kind of kidney problem can be treated well if detected and treated in the initial stage.

Can I Have Sex If I Have Kidney Failure

Can I Have Sex If I Have Kidney Failure
Sexual intercourse plays a crucial role in keeping a good relationship between lovers; however, once an individual is diagnosed with kidney failure, he and his partner will be worried whether their sexual intercourse will be affected.

Can kidney failure patients have sex?

Actually, whether a kidney failure patient can have sex depends on his illness condition very much. Generally speaking, if the patient is in good mind and has enough energy, they can have sex, but please remember to pay attention to the frequency. Affected kidneys fail to secrete a hormone called EPO , which can cause anemia. One of the major symptoms of renal anemia is fatigue and shortness of breath. Because of this, reducing frequency of sexual intercourse to avoid being exhausted is very necessary.

Besides, if kidney failure patients have sever complications like pulmonary edema and heart failure, they are not suggested to have sex, as it will increase their mortality.

What are the Causes of Chronic Renal Failure

There are a variety of diseases and pathological conditions that can cause chronic renal failure. The following are the main causes.

glomerular diseases including IgA nephropathy, FSGS, diabetic nephropathy, hypertensive nephropathy, lupus nephritis, etc.

chronic pyelonephritis, uric acid nephropathy, obstructive nephropathy as well as kidney damages due to long term intake of certain drugs such as aristolochic acid nephropathy.

renal vascular diseases such as aneurysm, renal artery embolization, renal thrombus and renal arteriovenous fistula, etc.

hereditary kidney diseases such as polycystic kidney disease(PKD) and hereditary nephritis, etc.

Diabetic nephropathy and hypertensive arteriolosclerosis and in developing countries these two causes still follow primary glomerulonephritis. Ischemic nephropathy due to bilateral renal artery stenosis or occlusion is one important cause of chronic renal failure especially in elderly patients.

Can I Bear a Baby If I Have Polycystic Kidney Disease(PKD)

PKD can be subdivided into two types---autosomal resessive PKD and autosomal dominant PKD according to different inheritary modes. The former is also called childhood PKD. It is rare in clinic and it usually occurs hours or days after birth. The later is also called adult PKD and it can occur to any age thought it is often found in people that are between 30s to 50s because during this period the cysts will experience rapid growth and cause a series of clinical symptoms and complications.

In case of ARPKD, it is rare in clinical and only when both parents carry the abnormal gene can the children have the disease and the incidence is 25%; in case of ADPKD, it has higher incidence than that of ARPKD because the disease can be inherited with one gene.

So for ADPKD patients, can they be pregnant and can they have a healthy baby without affecting the gravida’s health. If only the gravida has PKD and her husband is healthy, the child has 50% incidence to inherit the disease; if both the gravida and her husband has the disease, then they have at most 25% to have a healthy baby.

The next question is will the pregnancy affect the gravida’s health and safety. Actually this is up to the gravida’s current illness and physical conditions. If she has no high blood pressure and other health issues and the kidney functions have not been severely affected, then she can give birth to the baby. However she needs to have regular checks and have close monitoring of illness progression. However if the gravida has high blood pressure, diabetes or the kidney functions have been damaged, it is not a proper time to have baby. She needs to first bring the illness condition under control and then choose another suitable time under the doctors’ permission and guidance.

What are the Causes of Nephrotic Syndrome

For people with Nephrotic Syndrome, they release massive protein in urine and form proteinuria. Proteinuria is the dominant symptom of Nephrotic Syndrome and it can cause edema, hypoalbuminemia and hyperlipidemia directly.

Protein is the essential nutrition of our body and can be divided into different types. Kidneys are responsible for filtering blood and when protein flow into kidney with blood, glomerular filtration membrane perform function to protect them from being leaked. Therefore, in normal cases, no protein be detected out in urine.

However, for people with Nephrotic Syndrome, their filtration membrane is damaged and protein can pass through casually. When protein flow through membrane and flow out of our body with urine, proteinuria is formed. Without timely and effective control, more and more protein leak out, as a result of which, protein content in blood decreases. Hypoalbuminemia refers to the illness condition where levels of albumin in blood serum are abnormally low.

Besides, because of great loss of protein in urine, plasma osmotic pressure decreases. Under such a conditon, fluid in blood ooze and into surrounding tissues. Edema is caused when there is an abnormal accumulation of fluid in the interstitium.

Hyperlipidemia means high lipid level in blood and it also can be caused by serious loss of protein from urine. We know protein is the irreplaceable nutrition of our body. When large amounts of protein are lost from urine, our liver will produce some protein to meet our physical demand. When liver synthetizes protein, lipid is produced at the same time. For Nephrotic Syndrome patients, because of severe shortage of protein, their liver has to work continuously to produce protein. When this condition lasts for a long time, lipid content in blood increases and hyperlipidemia is caused.

Vomit in People with Nephrotic Syndrome

There is a variety of diseases and conditions which can contribute to vomiting in nephrotic syndrome.The detailed causes will be explained as follows.

Edema

Edema is one of typical signs of nephrotic syndrome. In serious case,fluid can build up in gastrointestinal tract. It also can make the patients with nephrotic syndrome vomit.

Waste products

As renal function declines, metabolic waste products and toxins can not be eliminated from body adequately. The waste products in intestinal tract can irritate mucosa, thus giving rise to vomiting in nephrotic syndrome.

Electrolyte imbalance

One of important kidney functions is to keep the balance of different types of minerals in body by removing extra minerals like sodium,potassium etc from body. However, if the kidneys are impaired, they fail to balance the electrolyte balance. Electrolyte imbalance can cause vomiting in nephrotic syndrome.

Side effects of some medications

A number types of medications will be prescribed to treat nephrotic syndrome. Steroids and immunosuppressive drugs are the most commonly used medications for the disease. Vomiting can be a side effect of certain kinds of medications.

Exercises for People with Nephrotic Syndrome

Nephrotic syndrome patients have varying degrees’ heart failure and it will be more serious of complicated with hypertension and anemia. One good way to control blood pressure is persistent proper exercises which can help patients lose weight and improve the heart functions. What is more, anemia can also be improved through exercises which can help increase the function of hemoglobin.

For those that have been taking long time dialysis, the lack of active vitamin D will cause renal osteopathy. The vitamin D in the foods can not be used by the body because the enzyme for transforming into active vitamin D is inhibited. The supplement of active vitamin agent has the risk of causing hypercalcemia. Therefore it is a good choice to take outdoor sports and sunbath which can help form natural active vitamin D through photochemical synthesis and lower the incidence of renal osteopathy.

It is common that nephrotic syndrome patients will have skin itching especially among elderly people. To prevent itchy skin, patients can take proper exercises besides thorough dialysis, proper bath and avoidance of certain excitant foods. Sweating after exercises with skin massage can help excrete toxins and promote blood circulation.

Then what are the exercises that are suitable for them? Proper exercises are conducive for them, but they should avoid strenuous exercises or over-tiredness. Mild and relaxed exercises such as walking, tai chi and qi gong are all good choices, which can help alleviate the symptoms, build up physical strength, reduce the incidence of catching cold, protect renal functions and reduce the risk of osteoporosis.

Can Cranberry and Pomegranate Help Lower High Creatinine Level

Kidney disease patients with high creatinine level should have more foods that contain rich vitamins especially vitamin A, vitamin B2 and vitamin 3. Fresh vegetables and fruits can be said to be the best resources. A study published in Turkey found that the supply of vitamin C can reduce creatinine level in rats with kidney diseases. This is because vitamin C has protective and oxidative effects. However for healthy people, supply of vitamin C can increase creatinine level.

We know that healthy renal diets have some certain restrictions such as low-protein and limitations on sodium, potassium, phosphorus and fluid. Therefore there are some foods and drinks that should be avoided or limited by them.

Here I recommend two kinds of fruits that are conducive for protecting kidney functions so as to reduce creatinine. One is cranberry and the other is pomegranate.

It has found that cranberry juice can help promote normal kidney functions and prevent developing kidney-related healthy problems. The most prominent effects are preventing urinary tract infections and kidney stones which are very common in kidney diseases and will further worsen kidney conditions if not treated properly and timely. Pomegranate has the similar effects as cranberry.

Both cranberry and pomegranate contain a lot of sugar, therefore the intake should be moderate to avoid too much body weight. And for those that have high blood sugar level, a dietitian or nutritionist should be consulted.